Interstitial cystitis - intravesical treatment

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Interstitial cystitis intravesical therapy

Interstitial cystitis (IC) is a progressive bladder disorder that presents with symptoms of bladder urgency, frequency and pain. The aetiology of the disease remains uncertain, but it is postulated that there is an initial infective insult which damages the glycosaminoglycan (GAG) layer of the bladder urothelium. This defect allows an influx of ions, particularly potassium, which initiates an i...

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Intravesical Bacillus Calmette-Guerin for treatment of refractory interstitial cystitis.

INTRODUCTION The aim of this study was to examine the efficacy and safety of intravesical Bacillus Calmette-Guerin (BCG) in the treatment of refractory interstitial cystitis (IC). MATERIALS AND METHODS Thirteen patients with refractory IC were enrolled in the study. They were scheduled to receive 6 weekly courses of treatment with intravesical BCG. Variables including the frequency, nocturia,...

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Intravesical chondroitin sulphate for interstitial cystitis/painful bladder syndrome

INTRODUCTION Interstitial cystitis/painful bladder syndrome (IC/PBS) is a chronic inflammatory condition of the bladder. Bladder instillation is one avenue of treatment but evidence for its effectiveness is limited. Chondroitin sulphate solution 2.0% (Urocyst) is a glycosaminoglycan (GAG) replenishment therapy instilled for patients with IC/PBS. We assessed its effectiveness for treating IC/PBS...

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Intravesical dimethyl sulfoxide (DMSO) for interstitial cystitis--a practical approach.

OBJECTIVES To provide a brief overview of intravesical dimethly sulfoxide (DMSO) therapy for interstitial cystitis and offer a practical approach to patient treatment. METHODS A review of the literature and a summation of the experience with treatment of > 300 patients with DMSO at the Interstitial Cystitis Clinic, New England Medical Center. RESULTS DMSO is helpful in a significant number ...

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Cochrane Review: Intravesical Treatments for Bladder Pain Syndrome/ Interstitial Cystitis

Hypothesis / aims of study Painful bladder syndrome (PBS) is defined by the International Continence Society (ICS) as “the complaint of suprapubic pain in relation to bladder filling, accompanied by other symptoms such as increased daytime and night-time frequency, in the absence of proven urinary tract infection or other obvious pathology”. ICS reserves its diagnosis of interstitial cystitis (...

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ژورنال

عنوان ژورنال: Revista da Associação Médica Brasileira

سال: 2019

ISSN: 1806-9282,0104-4230

DOI: 10.1590/1806-9282.65.4.535